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DeCS

Descriptor English:

tau Proteins

Descriptor Spanish:

Proteínas tau

Descriptor Portuguese:

Proteínas tau

Synonyms English:

Protein, tau
Proteins, tau
tau Protein

Tree Number:

Definition English:

Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

See Related English:

History Note English:

1992; use TAU (NM) 1977-91

Allowable Qualifiers English:

Record Number:

30290

Unique Identifier:

D016875

Similar:

DeCS